The mosquito population control in the larval stage is much easier than in the adult stage, and then new strategies are needed for controlling the proliferation of the larvae of A. This is not an easy task because the mosquitoes have developed resistance to the current synthetic insecticides that, in addition, are toxic to humans and the environment.

Today, the only way of decreasing the incidence of this disease is by controlling the Aedes aegypti proliferation. 3 Although some viral diseases, such as yellow fever, have been brought reasonably under control with a vaccine, no vaccine is so far available for dengue. 2 The disease has high levels of mortality, and also inflicts great economic losses and social disruption in Brazil. 1 Between 50 and 100 million of cases are registered each year, causing thousands of deaths. A composiГ§ГЈo quГmica do Гіleo essencial e as atividades descritas sГЈo comunicadas pela primeira vez.ДЄedes aegypti is the principal mosquito vector of dengue fever, including the hemorrhagic form, which is endemic to South East Asia, Central and South America, and West Africa. leptopetala Г© fonte potencial de larvicidas naturais. Os Гіleos essenciais das folhas e galhos tambГ©m mostraram atividade com CL 50 104,7 В± 0,2 and 34,7 В± 0,3 ppm, respectivamente. O extrato metanГіlico mostrou-se ativo com CL 50 64,6 В± 1,5 ppm e uma forte atividade foi exibida para o composto ( 1), CL 50 3,6 В± 0,4 ppm. Fries (Annonaceae) e as atividades larvicidas dos Гіleos essenciais, do extrato metanГіlico das raГzes desta espГ©cie e do alcalГіide oxoaporfinico, liriodenina ( 1), frente Г s larvas no terceiro estГЎgio do mosquito Aedes aegypti. No presente trabalho descreve-se a composiГ§ГЈo quГmica dos Гіleos essenciais de Rollinia leptopetala R.E. Keywords: Rollinia leptopetala, Annonaceae, essential oils, liriodenine, Aedes aegypti This is the first report about the chemical composition and larvicidal activity of the leaf and stem essential oils of R. leptopetala as a source of natural larvicidal compounds. The essential oils from the leaves and stems, also exhibited larvicidal activity with LC 50 104.7 В± 0.2 and 34.7 В± 0.3 ppm, respectively. Higher activity was observed for the isolated alkaloid liriodenine ( 1), LC 50 3.6 В± 0.4 ppm. The methanol extract from the roots showed larvicidal activity with LC 50 64.6 В± 1.5 ppm.

Fries (Annonaceae) and to evaluate the larvicidal activities of these essential oils, of the methanol extract from roots of this plant and of the oxoaporphine alkaloid, liriodenine ( 1) against the third-instar of Aedes aegypti larvae. The aim of present study was to describe the chemical composition of the essential oils from the leaf and stem of Rollinia leptopetala R.

IVSetor de QuГmica de Produtos Naturais, LCQUI-CCT, Universidade Estadual do Norte Fluminense, 28013-603 Campus-RJ, Brazil IIIDepartamento de QuГmica AnalГtica e FГsico-QuГmica, Universidade Federal do CearГЎ, CP 12100, 60451-670 Fortaleza-CE, Brazil IIDepartamento de FarmГЎcia, Universidade Federal do CearГЎ, Rua CapitГЈo Francisco Pedro 1210, 60430-370 Fortaleza-CE, Brazil IDepartamento de QuГmica OrgГўnica e InorgГўnica, Universidade Federal do CearГЎ, CP 6044, 60455-970 Fortaleza-CE, Brazil de Oliveira I Jackson Nunes e Vasconcelos I Jefferson Q. , Universidade Estadual do Norte Fluminense, Brazil About the authorsД¬hemical composition and larvicidal activity of Rollinia leptopetala (Annonaceae)Д®dinilza M. , Universidade Federal do CearГЎ, Departamento de QuГmica AnalГtica e FГsico-QuГmica, Brazil Raimundo Braz-Filho , Universidade Federal do CearГЎ, Departamento de QuГmica OrgГўnica e InorgГўnica, Brazil Ronaldo F. , Universidade Federal do CearГЎ, Departamento de QuГmica OrgГўnica e InorgГўnica, Brazil Grazielle T. , Universidade Federal do CearГЎ, Departamento de QuГmica OrgГўnica e InorgГўnica, Brazil Jefferson Q. , Universidade Federal do CearГЎ, Departamento de QuГmica OrgГўnica e InorgГўnica, Brazil Jackson Nunes e Vasconcelos , Universidade Federal do CearГЎ, Departamento de QuГmica OrgГўnica e InorgГўnica, Brazil M. , Universidade Federal do CearГЎ, Departamento de FarmГЎcia, Brazil Telma L. , Universidade Federal do CearГЎ, Departamento de QuГmica OrgГўnica e InorgГўnica, Brazil , Universidade Federal do CearГЎ, Departamento de QuГmica OrgГўnica e InorgГўnica, Brazil Gilvandete M. , Universidade Federal do CearГЎ, Departamento de QuГmica OrgГўnica e InorgГўnica, Brazil Г‚ngela M.

Nucleo forte composition